AudioParam: метод setValueAtTime()

setValueAtTime(value, startTime)

// create audio context
const audioCtx = new AudioContext();

// set basic variables for example
const myAudio = document.querySelector("audio");
const pre = document.querySelector("pre");
const myScript = document.querySelector("script");

pre.textContent = myScript.textContent;

const targetAtTimePlus = document.querySelector(".set-target-at-time-plus");
const targetAtTimeMinus = document.querySelector(".set-target-at-time-minus");

// Create a MediaElementAudioSourceNode
// Feed the HTMLMediaElement into it
const source = audioCtx.createMediaElementSource(myAudio);

// Create a gain node and set its gain value to 0.5
const gainNode = audioCtx.createGain();
gainNode.gain.value = 0.5;
let currGain = gainNode.gain.value;

// connect the AudioBufferSourceNode to the gainNode
// and the gainNode to the destination
source.connect(gainNode);
gainNode.connect(audioCtx.destination);

// set buttons to do something onclick
targetAtTimePlus.onclick = () => {
  currGain += 0.25;
  gainNode.gain.setValueAtTime(currGain, audioCtx.currentTime + 1);
};

targetAtTimeMinus.onclick = () => {
  currGain -= 0.25;
  gainNode.gain.setValueAtTime(currGain, audioCtx.currentTime + 1);
};